Packaging can be defined as an economical means information,
presentation, protection, identification, information, containment, convenience
and compliance for a product during storage carriage display and use until such
time as the product is used or administered.
Parts of the package:
- Container
- Closure
A container may be defined as a device in which the drug is
enclosed and is in direct contact with the drug.
Closure
A closure is a device as a seals the container to exclude O2
, CO2 , moisture , micro organisms and prevent the loss of
volatile substances. It also prevents the loss of medicament during transport
and handling.
Other component part
Primary Package/
Container
Is the immediate container which direct contact with the
drugs. Resist chemical.
Secondary
Package/Container
Is the outer container may be outer rapper. It is not
directly contact with the drug.
Characteristic of
container and closures
- The container must be sufficient strong to withstand handling while empty, when filling, closing, sterilizing, labeling, transport, storage and use by the consumer.
- They should not allow any and loss of product due to leakage, spoilage or permeation.
- The material of the container from which they are prepared must not react with the contents.
- They must be able to withstand heat if process includes sterilization by heat.
- They surface of the container must be clear for easy labeling.
- The container must not absorb substances from the preparation.
- The container must not impart its own color, taste and odor to the preparation.
- The container and closure must not react either with each other or with the preparation.
- The container should be able to protect light sensitive preparation for which amber colored glass containers may be used.
- The size of the container must be selected according to the size of the preparation.
- The closure must be easy to remove and replace.
- The cost of container and closure is an integral part of overall cost of the preparation, so it should not be high.
-
A container should facilitate the identification
of a product. Whether meant for internal or external use.
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